New sesquilignans from Arctium lappa L. The structure of lappaol C, D and E.
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چکیده
منابع مشابه
Small Molecule Therapeutics Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L
In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, fromplantArctiumLappaL. Lappaol F suppressed cancer cell growth in a timeanddose-dependent manner inhumancancer cell lines of various tissue types.We found thatLappaol F inducedG1 andG2 cell-cycle arrest, which was associated with strong induction of p21 and p27 and reduction of...
متن کاملLappaol F, a novel anticancer agent isolated from plant arctium Lappa L.
In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, from plant Arctium Lappa L. Lappaol F suppressed cancer cell growth in a time- and dose-dependent manner in human cancer cell lines of various tissue types. We found that Lappaol F induced G(1) and G(2) cell-cycle arrest, which was associated with strong induction of p21 and p27...
متن کامل1 Lappaol F , a novel anticancer agent isolated from plant Arctium Lappa
Correspondence: Ying Huang, M.D., Ph.D. Department of Pharmacology, State University of New York, Upstate Medical University 750 E. Adams Street Syracuse, New York 13210, USA. Email: [email protected] CoCorrespondence: Yingjie Hu, Ph.D. Laboratory of Chinese Herbal Drug Discovery, Tropical Medicine Institute, Guangzhou University of Chinese Medicine, 12 Jichang Road, Guangzhou 510405, China. E...
متن کاملArctigenin: a lignan from Arctium lappa
The title compound {systematic name: (3R-trans)-4-[(3,4-dimethoxy-phen-yl)meth-yl]-3-[(4-hydr-oxy-3-methoxy-phen-yl)meth-yl]-4,5-dihydrofuran-2(3H)-one}, C(21)H(24)O(6), has a dibenz-yl-butyrolactone skeleton. The two aromatic rings are inclined at a dihedral angle of 68.75 (7)° with respect to each other. The lactone ring adopts an envelope conformation. A series of O-H⋯O and C-H⋯O hydrogen bo...
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Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material s...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1977
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.41.1813